Hotel Republic San Diego, Autograph Collection

421 West B Street, Downtown San Diego, San Diego, United States - Vibrant restaurant scene

The luxury Hotel Republic San Diego, Autograph Collection is located 7 minutes' walk from Spreckels Theatre, in the center of San Diego, and offers rooms with town views. Featuring a restaurant and a lobby area, the 4-star modern hotel is located in the vicinity of Little Italy.

Location

The smoke-free hotel lies in the entertainment district of San Diego with easy access to American Plaza, which is 750 feet away. The Republic San Diego, Autograph Collection is also 25 minutes by foot from The San Diego Museum of Art in San Diego. The lush park "Botanical Building" is 1.5 miles away, and Santa Fe Depot is situated in the immediate vicinity of this accommodation. Courthouse city rail is about 10 minutes' walk away, while India St & C St bus stop is within 5 minutes' walk of the hotel.

Rooms

The Republic San Diego, Autograph Collection offers 284 rooms with tea and coffee-making facilities, and such modern conveniences as a flat-screen TV with satellite channels. Bathrooms with a separate toilet and a shower, also feature hairdryers and bathrobes for guests' extra comfort.

Food & Drinks

This property features a lounge bar and Trade restaurant serving American cuisine.

Leisure & Activities

Hotel Republic San Diego, Autograph Collection offers guests the opportunity to stay active with yoga instruction, elliptical machines, and treadmills. Guests can keep fit during their stay as the San Diego hotel has a fitness room featuring yoga classes.

Why choose Hotel Republic San Diego, Autograph Collection

Select room
  • Gaslamp Quarter entertainment nearby

  • SoCal-inspired rooftop dining

  • 24-hour fitness center access

  • Pet-friendly accommodations available

Main amenities

  • Free Wi-Fi

  • Parking

  • 24-hour services

  • Express check-in/ -out

  • Fitness/Gym

  • On-site Dining

  • Meeting facilities

  • Child-friendly

  • Wheelchair access

  • Air conditioning

  • Pets

General
  • Free Wi-Fi
  • Parking
  • 24-hour services
  • Express check-in/ -out
  • Fitness/Gym
  • On-site Dining
  • Meeting facilities
  • Child-friendly
  • Wheelchair access
  • Air conditioning
  • Pets
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Internet

  • Free Wi-Fi
  • Free Wi-Fi in rooms

Parking options

  • Parking
  • Valet parking

Activities

  • Fitness centre
  • Yoga class

Property services

  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Security
  • Luggage storage
  • Pet amenities available
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink
  • Happy hour

Dining options

  • Restaurant
  • Bar/ Lounge area

Business facilities

  • Meeting/ Banquet facilities
  • Fax/Photocopying

For kids

  • Cots
  • Children's menu

Recreation

  • Live entertainment
  • Leisure/ TV room

For disabled guests

  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Toilet for disabled
  • Bathroom for disabled

In the rooms

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

In the bathroom

  • Free toiletries

Devices

  • Flat-screen TV
  • AM/FM alarm clock

Design

  • Carpeted floor

General facilities

  • No smoking on site
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Pets

  • Pets allowed

Important information

Check-in:
from 16:00 until 23:59
Check-out:
until 11:00
  • Children and extra beds
  • There are no extra beds provided in a room.
  • There are no cribs provided in a room.

Enter dates to see availability

From USD 126 per night
Check-in 24 Feb 2026
Check-out 25 Feb 2026
Guests 2 guests

Adults:

2

Children:

0

Rooms

Photos of Hotel Republic San Diego, Autograph Collection

Location of Hotel Republic San Diego, Autograph Collection

421 West B Street, Downtown San Diego, San Diego, United States

 -  Vibrant restaurant scene
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    335 reviews

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    100% Verified Reviews
    Enter dates to see availability
    From USD 126 per night
    Check-in 24 Feb 2026
    Check-out 25 Feb 2026
    Guests 2 guests

    Adults:

    2

    Children:

    0
    Check-in & out
    24 Feb 2026
    25 Feb 2026
    Guests
    2 guests
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    Hotel Republic San Diego, Autograph Collection
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    Details:

    421 West B Street, San Diego, United States

    Important information
    Hotel Republic San Diego, Autograph Collection
    Check-in:
    from 16:00 until 23:59
    Check-out:
    until 11:00
    • Children and extra beds
    • There are no extra beds provided in a room.
    • There are no cribs provided in a room.